ISRIB is an integrated stress response (ISR) inhibitor which reverses the effects of eIF2 phosphorylation and inhibits eIF2α phosphorylation-induced stress granule (SG) formation. When administered to mice, ISRIB enhances cognition and limits cognitive decline due to brain injury.
Researchers studied the activity and anatomy of cells in the hippocampus, a brain region with a key role in learning and memory, just one day after giving animals a single dose of ISRIB. They found that common signatures of neuronal aging disappeared literally overnight: neurons’ electrical activity became more sprightly and responsive to stimulation, and cells showed more robust connectivity with cells around them while also showing an ability to form stable connections with one another usually only seen in younger mice.
ISRIB powder (1g)
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Safety Information: Keep this product out of the reach of children. This product is not a dietary supplement. It is a research compound, sold as a raw material. It may result in adverse effects if improperly handled or consumed. This product is for use and handling only by persons with the knowledge and equipment to safely handle this material.
Cymnootropics.com can’t be held responsible for any adverse effects that may arise from improper handling and/or consumption of this product.
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